Case for Interferon by Joseph Cummins

Author:Joseph Cummins
Language: eng
Format: epub
ISBN: 9781510765511
Publisher: Skyhorse
Published: 2020-02-14T16:00:00+00:00

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In the summer of 1989, I flew to Japan to discuss a license to acquire a natural human interferon made by HBL in Okayama. Mr. Katsuaki Hayashibara and five other men met with me for several hours to discuss my research with oral human interferon and the process used for producing it. I sought a license and supply agreement to use their human interferon for oral administration by offering to pay them more than they were receiving for their injectable human interferon. At the end of the day, Mr. Hayashibara proposed that I take some of their human interferon and test it orally in cattle to see if it worked. I accepted his proposal and took the product in my pocket to Texas.

Experimental light-weight feeder calves were waiting in Texas. Within days, twelve calves were inoculated with IBR virus, and some of them were given the low-dose oral human interferon from Japan. The treatment reduced the fever and resulted in better weight gain, compared to control calves. I faxed the results to HBL and asked again for the opportunity to license their human interferon.

At their request, a license proposal was sent, and I was invited to return to Japan.

When I entered the meeting room in Okayama for the second time, Mr. Katsuaki Hayashibara took me aside and told me that Mr. Ken Hayashibara (HBL’s president and his cousin) liked the oral human interferon technology I’d pioneered.

He added that Ken wanted “to invest” and asked, “Would that be possible?”

I was surprised by his statements. I felt I’d just been sharing my work, not pitching them for an investment. At the time I’d been funding my human interferon research with investments from Dennis Moore and other investors in ACC. I felt I barely had two nickels to rub together. I was a science guy, not a corporate money strategist.

I’d been down that road many times before and had failed spectacularly. I couldn’t interest any American companies in what I was doing, so I figured that wasn’t in the cards.

However, even with my enormous blind spot as to what was really happening, I was able to stammer out, “Yes, that would be possible.”

As the discussion went on, I finally asked, “Have you tested oral human interferon?”

“Yes,” they responded, and one of the men hurried from the room and returned with their special white powdered sugar preparation (crystalline anhydrous maltose [ACM]) and HBL human interferon that HBL scientists had been testing.

Unlike the sixty companies in the United States I’d approached, who’d rejected my technology without testing, HBL had tested oral human interferon and liked the results. Mr. Ken Hayashibara told me that “corns” came off his feet after he tried oral human interferon.

While in Japan, I agreed to the sale of 10 percent of ABI’s stock to HBL at the lowest price I thought my Board of Directors would accept (I chose the option price then held by the colorful T. Boone Pickens). These men had not heard of T. Boone Pickens. But by

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